3-Oxo-hop-22(29)-ene

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CAS NO:

25615-11-6

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

3-Oxo-hop-22(29)-ene 是一种yeast α-glucosidase抑制剂。3-Oxo-hop-22(29)-ene 具有中等的抗克氏锥虫和抗墨西哥利什曼原虫活性。3-Oxo-hop-22(29)-ene 具有微弱的抗炎活性。

生物活性

3-Oxo-hop-22(29)-ene is ayeast α-glucosidaseinhibitor. 3-Oxo-hop-22(29)-ene shows a moderate effect on the viability ofT. cruziandL. mexicana. 3-Oxo-hop-22(29)-ene shows marginal activity of anti-inflammatory^[1].

体外研究
(In Vitro)

3-Oxo-hop-22(29)-ene (compound 2) (50 μM; 24 hours) reduces the viability ofT. cruziby more than 20%, and has a moderate effecton onT. rangeliandL. mexicana^[1].
3-Oxo-hop-22(29)-ene (10, 100 μM; 48 hours) causes 1.51% and 7.39% inhibition activity to yeast α-glucosidase respectively^[1].

Cell Viability Assay^[1]

Cell Line:	Saccharomyces cerevisiae (type 1) and mammalian yeast (type 2) α-glucosidases,T. cruzi,T. rangeli,L. mexicana
Concentration:	10 μM, 50 μM, 100 μM
Incubation Time:	24 hours, 48 hours
Result:	Reduced the viability ofT. cruziby more than 20%, and had a moderate effecton onT. rangeliandL. mexicana Inhibited Yeast α-glucosidase.

体内研究
(In Vivo)

3-Oxo-hop-22(29)-ene (0.31 μmol/ear; application; once) decreases 17.50 % the inflammation of mouse ear edema model^[1].

Animal Model:	Adult male CD-1 mice (25-30 g) (Mouse ear edema model induced by 12-O-tetradecanoylphorbol acetate (TPA))^[1]
Dosage:	0.31 μmol/ear
Administration:	Apply to both faces of the right ear; once
Result:	Decreased 17.50% the inflammation of mouse ear edema model.

分子量

424.70

Formula

C₃₀H₄₈O

CAS 号

25615-11-6

结构分类

Terpenoids
Triterpenes

来源

Plants
Euphorbiaceae
Cnidoscolus spinosusLundell

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.