| CAS NO: | 2368978-96-3 |
| 包装 | 价格(元) |
| 5mg | 电议 |
| 10mg | 电议 |
| Cas No. | 2368978-96-3 |
| 别名 | NBL-SS perchlorate |
| Canonical SMILES | O=C(NC1=CC(OC2=C/3)=C(C4=C1C=CC=C4)N=C2C=CC3=[N+](CCC(OC)=O)/CCC(OC)=O)OCCSSCCO.O=Cl(=O)([O-])=O |
| 分子式 | C29H32ClN3O12S2 |
| 分子量 | 714.16 |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (Λex=615 nm, Λem=661 nm)[1]. Trx-red (NBL-SS) displayed multiple favorable properties, such as red emission, fast response, and high fluorescence signal. Thioredoxin (Trx) is a ubiquitous redox-regulating protein essentially involved in cell growth, differentiation, and death[1]. When HeLa cells are incubated with Trx-red (NBL-SS; 5 μM; 0-30 min), a clear time-dependent increase of the fluorescence is observed[1]. Trx-red (NBL-SS; 10 μM; 30 min) is also suitable to image thioredoxin in 6 day-old zebrafish larvae[1]. [1]. Huiyi Jia, et al. Fluorophore-Dependent Cleavage of Disulfide Bond Leading to a Highly Selective Fluorescent Probe of Thioredoxin. Anal Chem. 2019 Jul 2;91(13):8524-8531. |
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