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5-Geranoxy-7-methoxycoumarin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
5-Geranoxy-7-methoxycoumarin图片
CAS NO:7380-39-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品介绍
5-Geranoxy-7-methoxycoumarin 是一种具有抗癌、抗真菌和抗菌活性的香豆素。5-Geranoxy-7-methoxycoumarin 诱导细胞凋亡(apoptosis)。
生物活性

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cellapoptosis[1][2].

体外研究
(In Vitro)

5-Geranoxy-7-methoxycoumarin (12.5-200 μM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 μM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 μM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

Cell Proliferation Assay[1]

Cell Line:SW480
Concentration:0-20 μM
Incubation Time:24, 48 and 72 hours
Result:Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line:SW480 cells
Concentration:50 μM
Incubation Time:48 hours
Result:Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line:SW480 cells
Concentration:50 μM
Incubation Time:48 hours
Result:Inhibited cell cycle progressionin vitro.
分子量

328.40

Formula

C20H24O4

CAS 号

7380-39-4

结构分类
  • Phenylpropanoids
  • Coumarins
来源
  • Plants
  • Rutaceae
  • Citrus limon(L.) Burm. F.
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.