CAS NO: | 2451298-06-7 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | P-gp inhibitor 5 is a potentP-glycoprotein(P-gp)inhibitor. P-gp inhibitor 5 has antiproliferative activity against certaincancercell lines. P-gp inhibitor 5 is effective in reversing the multidrug resistance (MDR) phenotype in ABCB1/Flp-InTM-293 and KBvin cells by restoring their sensitivity to Vincristine (HY-N0488A) and Paclitaxel (HY-B0015)[1]. |
IC50& Target | P-gp[1] |
体外研究 (In Vitro) | P-gp inhibitor 5 (compound 10) has cytotoxic against ABCB1/Flp-InTM-293 and KBvin cells with IC50s of 29.7 and 12.6 μM, respectively[1]. |
分子量 | 517.98 |
Formula | C28H20ClNO5S |
CAS 号 | 2451298-06-7 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |