CAS NO: | 1795134-78-9 |
包装 | 价格(元) |
1mg | 电议 |
10mg | 电议 |
生物活性 | Toceranib-d8 (SU11654-d8) is the deuterium labeled Toceranib. Toceranib (SU11654) is an orally active receptor tyrosine kinase (RTK) inhibitor, and it potently inhibitsPDGFR,VEGFR, andKitwithKis of 5 and 6 nM forPDGFRβand Flk-1/KDR, respectively. Toceranib (SU11654) has antitumor and antiangiogenic activity, and used in the treatment of canine mast cell tumors[1][2]. |
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
分子量 | 404.51 |
Formula | C22H17D8FN4O2 |
CAS 号 | 1795134-78-9 |
中文名称 | 托西尼布 d8 |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |