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Pomalidomide-PEG1-azide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Pomalidomide-PEG1-azide图片
CAS NO:2133360-04-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
Pomalidomide-PEG1-azide 是一种 E3 连接酶配体-linker 偶联物。Pomalidomide-PEG1-azide 包含 cereblon 配体和linker,Pomalidomide-PEG1-azide 可用于设计 PROTAC BRD4 Degrader-1 。
Cas No.2133360-04-8
别名泊马度胺-PEG-1叠氮化物
分子式C17H16N6O6
分子量400.35
溶解度DMSO : 62.5 mg/mL (156.11 mM; ultrasonic and warming and heat to 60℃)
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Pomalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Pomalidomide-PEG1-azide incorporates the Pomalidomide based cereblon ligand and a linker. Pomalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-1 [1].

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.