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Lenalidomide-PEG1-azide
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lenalidomide-PEG1-azide图片
CAS NO:2185795-67-7
包装与价格:
包装价格(元)
50mg电议
100mg电议

产品介绍
Lenalidomide-PEG1-azide 是一种E3连接酶 lgand-linker 复合物。Lenalidomide-PEG1-azide 包含 cereblon 配体和 linker。Lenalidomide-PEG1-azide 可用于设计 PROTAC BRD4 Degrader-1 。
Cas No.2185795-67-7
分子式C17H18N6O5
分子量386.36
溶解度DMSO : 100 mg/mL (258.83 mM; Need ultrasonic)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Lenalidomide-PEG1-azide is a E3 ligase lgand-linker conjugate. Lenalidomide-PEG1-azide incorporates the Lenalidomide based cereblon ligand and a linker. Lenalidomide-PEG1-azide can be used to design a PROTAC BRD4 Degrader-2 [1].

[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide. Bioorg Med Chem. 2020 Jan 1;28(1):115228.