CAS NO: | 878006-06-5 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
5mg | 电议 |
10mg | 电议 |
50mg | 电议 |
100mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | (E)-[6]-Dehydroparadol, an oxidative metabolite of [6]-Shogaol (HY-14616), is a potentNrf2activator. (E)-[6]-Dehydroparadol can inhibit the growth and induce theapoptosisof humancancercells[1][2]. | ||||||||||||||||
IC50& Target | Nrf2[2] | ||||||||||||||||
体外研究 (In Vitro) | (E)-[6]-Dehydroparadol (M15) (5-80 μM; 24 h) inhibits the growth of HCT-116 and H-1299 cells, with IC50s of 43.02 and 41.59 μM, respectively[1]. | ||||||||||||||||
体内研究 (In Vivo) | (E)-[6]-Dehydroparadol (compound 19) (5 μM; 24 h) enhances Tg[glutathione S-transferase pi 1 (gstp1):green fluorescent protein (GFP)] fluorescence signal in the Tg(gstp1:GFP) transgenic zebrafish embryos[2]. | ||||||||||||||||
分子量 | 276.37 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C17H24O3 | ||||||||||||||||
CAS 号 | 878006-06-5 | ||||||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: DMSO : ≥ 140 mg/mL(506.57 mM) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 |