CAS NO: | 2772949-38-7 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | CB1/2 agonist 4 is a fullCB1agonist andCB2partial agonist withEC50values of 15.09 nM and 1.16 nM, respectively. CB1/2 agonist 4 also has hCB1 and hCB2 receptor affinities withKivalues of 1.1 nM and 4.2 nM, respectively. CB1/2 agonist 4 has a significant antinociceptive activity, and also can activate cannabinoid andTRPV1receptor with values ofIC50andEC50is 0.8 μM and 0.12 μM, respectively[1]. | ||||||||
IC50& Target | Ki: 1.1 nM (hCB1); 4.2 nM (hCB2)[1]. | ||||||||
体外研究 (In Vitro) | CB1/2 agonist 4 (compound 24) has hCB1 and hCB2 receptor affinities with Kivalues of 1.1 nM and 4.2 nM, respectively[1]. | ||||||||
体内研究 (In Vivo) | CB1/2 agonist 4 (compound 24) (1, 3 and 4 mg/kg, i.p.) has a stronger antinociceptive activity[1].
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分子量 | 431.65 | ||||||||
Formula | C27H45NO3 | ||||||||
CAS 号 | 2772949-38-7 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |