Phentolamine is a potent, selective and orally activeα1 adrenergicandα2 adrenergicreceptor antagonist. Phentolamine can be used for the treatment of erectile dysfunction^[1][2][3].

Phentolamine (5-20 mg/kg; i.p.) effectively inhibits the seizures elicited by strychnine (2 mg/kg, i.p.) and attenuates the seizure-potentiating effect of DOPS (4 mg/kg, i.p.) in mouse^[2].
Phentolamine (1 mg/kg; i.p.) increases insulin secretion by inhibition of b-cell a2A-adrenoceptors in mouse^[3].

281.35

C₁₇H₁₉N₃O

50-60-2

酚妥拉明

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.