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CypD-IN-4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CypD-IN-4图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
CypD-IN-4 是一种有效的亚型选择性亲环蛋白 D (CypD) 抑制剂。CypD-IN-4 具有亲环蛋白 D (CypD) 亲和力,IC50值为 0.057 μM。CypD-IN-4 可用于多种疾病的研究,如氧化应激、神经退行性疾病、肝病、衰老、自噬和糖尿病。
生物活性

CypD-IN-4 is a potent and subtype-selectivecyclophilin D (CypD)inhibitor. CypD-IN-4 has CypD affinity with anIC50value of 0.057 μM. CypD-IN-4 can be used for the research of several diseases including oxidative stress, neurodegenerative disorders, liver diseases, aging,autophagyand diabetes[1].

IC50& Target

IC50: 0.057 μM (CypD); 3.4 μM (CypA); 1.1 μM (CypB); 0.8μM (CypE)[1]

体外研究
(In Vitro)

CypD-IN-4 (B53) has selectivity for inhibiting CypD, CypA, CypB and CypE with IC50values of 0.057 μM, 3.4 μM, 1.1 μM and 0.8 μM, respectively[1].
CypD-IN-4 (20 μM) inhibits mitochondrial permeability transition pore opening in isolated mitochondria[1].

分子量

986.12

Formula

C54H63N7O11

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.