Triptolide-d3 (PG490-d3) is the deuterium labeled Triptolide. Triptolide is a diterpenoid triepoxide extracted from the root ofTripterygium wilfordiiwith immunosuppressive, anti-inflammatory, antiproliferative and antitumour effects. Triptolide is aNF-κBactivation inhibitor^{[1][2][3][4][5][6]}.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

363.42

C₂₀H₂₁D₃O₆

雷公藤甲素 d3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.