Colistin adjuvant-1 is acolistin adjuvant, shows increased colistin potentiation activity against Gram-negative bacteria. Colistin adjuvant-1 inhibitsNF-κBwith anIC₅₀of 0.209 μM^[1].

Colistin adjuvant-1 (compound 13) inhibits a panel of additional colistin-resistant strains ofK. pneumoniaeandA. baumannii, including strains harboring themcr-1gene, and also determined activity against colistin-resistant strains ofP. aeruginosa^[1].

414.23

C₁₆H₇F₉N₂O

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.