Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin (HY-B0589)^[1]. Atorvastatin is an orally activeHMG-CoA reductaseinhibitor, has the ability to effectively decrease blood lipids.

Atorvastatin treatment decreases apoptosis of myocardial cells by down-regulating GRP78, caspase-12 and CHOP expression in myocardial cells after myocardial infarction, and the endoplasmic reticulum (ER) stress is activated in response to heart failure and angiotensin II (Ang II) stimulation.

449.47

C₂₆H₂₄FNO₅

873950-19-7

阿托伐他汀钙杂质Atorvastatin Epoxy Tetrahydrofuran Impurity

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.