Dihydrochelerythrine

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CAS NO:

6880-91-7

包装与价格：

包装	价格(元)
10 mM * 1 mL in DMSO	电议
5mg	电议
10mg	电议
50mg	电议
100mg	电议

产品名称

二氢白屈菜红碱
12,13-Dihydrochelerythrine

产品介绍

二氢白屈菜红碱(Dihydrochelerythrine)是从延胡索分离出的天然化合物，具抗真菌等活性。

生物活性

Dihydrochelerythrine is a natural compound isolated fromCorydalis yanhusuo; has antifungal activity. IC50 value: Target: in vitro: Dihydrochelerythrine showed the highest antifungal activity against B. cinerea Pers, with 98.32% mycelial growth inhibition at 50 μg/mL. Dihydrochelerythrine inhibited spore germination in vitro in a concentration-dependent manner [1]. Dihydrochelerythrine appeared to be less cytotoxic since the viability of cells exposed to 20 microM dihydrochelerythrine for 24h was reduced only to 53%. A dose-dependent induction ofapoptosisand necrosis by chelerythrine and dihydrochelerythrine was confirmed by annexin V/propidium iodide dual staining flow cytometry [2]. Dihydrochelerythrine (4) exhibited strong activity against methicillin-resistant Staphylococcus aureus SK1 and moderate activity against Escherichia coli TISTR 780 with MIC values of 8 and 16 μg/mL, respectively [3].

分子量

349.38

性状

Solid

Formula

C₂₁H₁₉NO₄

CAS 号

6880-91-7

中文名称

二氢白屈菜红碱

结构分类

Alkaloids
Quinoline Alkaloids

来源

Plants
Papaveraceae
Macleaya cordata(Willd.) R. Br.

Plants
Papaveraceae
Corydalis yanhusuoW. T. Wang

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

DMSO : 20.83 mg/mL(59.62 mM;Need ultrasonic)

配制储备液

浓度溶剂体积质量

1 mg

5 mg

10 mg

1 mM	2.8622 mL	14.3111 mL	28.6221 mL
5 mM	0.5724 mL	2.8622 mL	5.7244 mL
10 mM	0.2862 mL	1.4311 mL	2.8622 mL

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。