Cefpiramide (SM-1652) free acid is a semisynthetic cephalosporin with broad-spectrum antibacterial activity. Cefpiramide free acid shows strong antibacterial effect on both gram-positive bacteria and gram-negative bacteria. Cefpiramide free acid is moderately susceptible to β-lactamase^[1][2].

Bacterial^[1][2]

Cefpiramide (0-2048 μg/mL; 16-18 hours) shows good activity to against most non-fermentative Gram-negative bacilli andEnterococci(32 μg/mL with 97% inhibition)^[1].
Cefpiramide (0-2048 μg/mL; 16-18 hours) exhibits high effective to againstPseudomonas aeruginosawith MIC_[50]and MIC_[90]values of 4 μg/mL and 16 μg/mL separately^[1].

Cefpiramide (25 mg/kg; i.v.; once) shows anti-Streptococcus pneumoniaeactivity in experimental pneumococcal meningitis^[2].
Cefpiramide (25 mg/kg; i.v.; once) reduces bacteria in CSF more than 10^[4]CFU/ml^[2].

612.64

C₂₅H₂₄N₈O₇S₂

70797-11-4

头孢匹胺游离酸

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.