您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Cephalexin(lysine)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Cephalexin(lysine)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Cephalexin(lysine)图片
CAS NO:53950-14-4
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品名称
Cefalexin (lysine)
Cephacillin (lysine)
产品介绍
Cephalexin (Cefalexin) lysine 是一种口服有效的新型半合成头孢菌素抗生素 (antibiotic),具有广泛的抗菌谱。Cephalexin lysine 对多种革兰氏阳性和革兰氏阴性细菌具有抗菌活性。Cephalexin lysine 靶向青霉素结合蛋白 (PBPs),以抑制细菌细胞壁组装。Cephalexin lysine 可用于肺炎、链球菌性咽喉炎、细菌性心内膜炎等的研究。
生物活性

Cephalexin (Cefalexin) lysine is a potent, orally active new semisynthetic cephalosporinantibioticwith a broad antibacterial spectrum. Cephalexin lysine has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin lysine targets penicillin-binding proteins (PBPs) to inhibitbacterialcell wall assembly. Cephalexin lysine is used for the research of pneumonia, strep throat, andbacterialendocarditis, et al[1][2].

IC50& Target

Bacteria[1]

体外研究
(In Vitro)

Cephalexin lysine (10 μg/mL) disrupts polymer peptidoglycan (PG) biogenesis by inactivating enzymes called penicillin-binding proteins (PBPs)[1].
Cephalexin lysine inhibits a broad spectrum of grampositive and gram-negative organisms with MIC values of 2, 2, 2, 2, 4, 4.4 and 5.7 μg/mL forBacillus anthracis,Edwardsiella taFda,Vibrio cholera,Pasteurella multocida,Edwardsiella tarda,Alcaligenes spandProteus rettgeri, respectively[2].

体内研究
(In Vivo)

Cephalexin lysine (0-50 mg/kg; p.o.; for 3.5 hours) has antibacterial activity in male Swiss-Webster mice with infected bacterial[2].

Animal Model:Male Swiss-Webster mice with infected bacterial[2]
Dosage:0-50 mg/kg
Administration:Oral administration; for 3.5 hours
Result:Had antibacterial activity againstStreptococcus pyogenes,Streptococcus pneumoniae,Staphylococcus aureusand severalgram-negative speciesmice.
Clinical Trial
分子量

493.58

Formula

C22H31N5O6S

CAS 号

53950-14-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.