Nalidixic Acid-d5 is the deuterium labeled Nalidixic acid. Nalidixic acid, aquinoloneantibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit ofDNA gyraseandtopoisomeraseIVand reversibly blocks DNA replication in susceptible bacteria^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

237.27

C₁₂H₇D₅N₂O₃

1189467-36-4

萘啶酸 d5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.