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Phillygenin(Phillygenol)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Phillygenin(Phillygenol)图片
CAS NO:487-39-8
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
5mg电议
10mg电议

产品介绍
Phillygenin (Phillygenol) 是连翘的活性成分,具有抗氧化、降低血脂、抑制低密度脂蛋白氧化等多种药用特性。
Cas No.487-39-8
别名连翘脂素; Phillygenol; Epipinoresinol methyl ether; (+)-Phillygenin
Canonical SMILESOC1=CC=C([C@H]2OC[C@@]3([H])[C@]2([H])CO[C@H]3C4=CC=C(OC)C(OC)=C4)C=C1OC
分子式C21H24O6
分子量372.41
溶解度DMSO : 50 mg/mL (134.26 mM);Water :< 0.1 mg/mL (insoluble)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Phillygenin is an active ingredient from Forsythia with many medicinal properties, such as antioxidant, reducing blood lipid, inhibition of low density lipoprotein oxidation.In vitro : 1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine.2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.In vivo: The reference for rat is 5.6 mg/m l ( i.v).

[1]. Ye LH et al. Determination of phillygenin in rat plasma by high-performance liquid chromatography and its application to pharmacokinetic studies. Eur J Drug Metab Pharmacokinet, 2013 Sep, 38(3):201-7. [2]. Song W et al. Interaction between phillygenin and human serum albumin based on spectroscopic and molecular docking. Spectrochim Acta A Mol Biomol Spectrosc, 2012 Jan, 85(1):120-6.