VUF 10166 是一种有效且高亲和力的 5-HT3 受体拮抗剂,其 Ki 值为 0.04 nM (5-HT3A) 和 22 nM (5-HT3AB)。
Cas No. | 155584-74-0 |
化学名 | 2-chloro-3-(4-methylpiperazin-1-yl)quinoxaline |
Canonical SMILES | CN1CCN(CC1)C2=NC3=CC=CC=C3N=C2Cl |
分子式 | C13H15ClN4 |
分子量 | 262.74 |
溶解度 | ≥ 26.3mg/mL in EtOH |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | VUF10166 is a novel, potent and competitive antagonist for 5-HT3A receptor with Kiof 0.04 nM, its affinity at 5-HT3AB receptor is significantly lower. |