| CAS NO: | 72025-60-6 |
| 包装: | 10µg |
| 市场价: | 2520元 |
白三烯 C4 是由 LTC4 合酶催化的谷胱甘肽与 LTA4 结合产生的母体半胱氨酰白三烯。
| Cas No. | 72025-60-6 |
| 别名 | 白三烯C4 |
| 化学名 | 5S-hydroxy-6R-(S-glutathionyl)-7E,9E,11Z,14Z-eicosatetraenoic acid |
| Canonical SMILES | CCCCC/C=C\C/C=C\C=C\C=C\[C@@H](SC[C@H](NC(CC[C@H](N)C(O)=O)=O)C(NCC(O)=O)=O)[C@@H](O)CCCC(O)=O |
| 分子式 | C30H47N3O9S |
| 分子量 | 625.8 |
| 溶解度 | 50mg/mL in DMSO, or in DMF |
| 储存条件 | Store at -80°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Leukotriene C4 (LTC4) is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. LTC4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism in platelets.[1] It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A) and exhibits potent smooth muscle contracting activity.[2] LTC4-induced bronchoconstriction and enhanced vascular permeability contribute to the pathogenesis of asthma and acute allergic hypersensitivity.[3],[4] The concentration of LTC4 required to produce marked contractions of lung parenchymal strips and isolated tracheal rings is about 1 nM.[4] Reference: |
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