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Tabersonine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Tabersonine图片
CAS NO:4429-63-4
包装与价格：
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
Tabersonine 是一种主要从蔷薇中分离出的吲哚类生物碱。Tabersonine 能破坏 Aβ(1-42) 的聚合和改善 Aβ 聚合诱导的细胞毒性。Tabersonine 具有抗炎活性，是潜在的治疗 ALI/ARDS 候选药物。
Cas No.4429-63-4
别名水甘草碱
Canonical SMILESO=C(OC)C1=C2NC3=CC=CC=C3[C@@]24CCN5CC=C[C@@]([C@@]45[H])(CC)C1
分子式C21H24N2O2
分子量336.43
溶解度DMF: 2 mg/ml,DMSO: 2 mg/ml,Ethanol: slightly soluble
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tabersonine is an indole alkaloid mainly isolated from Catharanthus roseus. Tabersonine disrupts Aβ(1-42) aggregation and ameliorates Aβ aggregate-induced cytotoxicity. Tabersonine has anti-inflammatory activities and acts as a potential therapeutic candidate for the treatment of ALI/ARDS[1].

[1]. Zhang D, et al. Tabersonine attenuates lipopolysaccharide-induced acute lung injury via suppressing TRAF6 ubiquitination. Biochem Pharmacol. 2018 Aug;154:183-192.