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IX 207-887
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
IX 207-887图片
CAS NO:98320-39-9
包装与价格:
包装价格(元)
250mg电议
500mg电议

产品介绍
IX207-887是一种新型抗关节炎药物,也能抑制白细胞介素-1(IL-1)的释放。
Cas No.98320-39-9
Canonical SMILESOC(/C=C1C2=C(SC=C2)C(OC)=CC3=C\1C=CC=C3)=O
分子式C16H12O3S
分子量284.33
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1).

IX 207-887 is a novel antiarthritic agent which inhibits the release of interleukin-1 (IL-1) from human monocytes and mouse peritoneal macrophages. In all test systems IX 207-887 significantly reduces both biologically active and immunoreactive IL-1 in culture media, whereas the levels of IL-1 in homogenates or lysates are either unaffected or only marginally reduced. IX 207-887 neither affects the adherence of human monocytes nor markedly inhibits IL-1 or IL-2-induced thymocyte proliferation. In the chondrocyte test no IL-1 antagonistic activity of IX 207-887 can be observed[1].

[1]. Schnyder J, et al. Inhibition of interleukin-1 release by IX 207-887. Agents Actions. 1990 Jun;30(3-4):350-62.