| CAS NO: | 1802226-78-3 |
| 包装 | 价格(元) |
| 10mM (in 1mL Water) | 电议 |
| 5mg | 电议 |
| 25mg | 电议 |
PSB-12379是一种有效的Ecto-5'-Nucleotidase(CD73)抑制剂，Kis值为9.03nM(鼠)和2.21nM(人)。
| Cas No. | 1802226-78-3 |
| Canonical SMILES | O[C@@H]([C@H]1O)[C@@H](COP(CP(O)(O)=O)(O)=O)O[C@H]1N(C=N2)C3=C2C(NCC4=CC=CC=C4)=NC=N3 |
| 分子式 | C18H23N5O9P2 |
| 分子量 | 515.35 |
| 溶解度 | Water : 7.14 mg/mL (13.85 mM);DMSO :< 1 mg/mL (insoluble or slightly soluble) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | PSB-12379 is a potent Ecto-5'-Nucleotidase (CD73) inhibitor with Kis of 9.03 nM (rat) and 2.21 nM (human). [1]. Bhattarai S, et al. α,β-Methylene-ADP (AOPCP) Derivatives and Analogues: Development of Potent and Selective ecto-5'-Nucleotidase (CD73) Inhibitors. J Med Chem. 2015 Aug 13;58(15):6248-63. |
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