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Mirtazapine
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Mirtazapine图片
CAS NO:85650-52-8
包装与价格：
包装价格(元)
10mM (in 1mL DMSO)电议
10mg电议
50mg电议

产品介绍
Mirtazapine (Org3770) 是一种有效且具有口服活性的去甲肾上腺素能和特异性 5-羟色胺能抗抑郁药 (NaSSA)。
Cas No.85650-52-8
别名米氮平
化学名2-methyl-1,2,3,4,10,14b-hexahydrobenzo[c]pyrazino[1,2-a]pyrido[3,2-f]azepine
Canonical SMILES[H]C1(C2=C([H])C([H])=C([H])C([H])=C2C([H])([H])C3=C4N=C([H])C([H])=C3[H])N4C([H])([H])C([H])([H])N(C([H])([H])[H])C1([H])[H]
分子式C17H19N3
分子量265.35
溶解度≥ 11.9mg/mL in DMSO
储存条件Store at 2-8°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mirtazapine is a 5-HT receptor inhibitor. Mirtazapine is a potent and orally active noradrenergic and specific serotonergic antidepressant (NaSSA) agent by blocking 5-HT2 and 5-HT3 receptors[1].

References:
[1]. Anttila, S.A. and E.V. Leinonen, A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev, 2001. 7(3): p. 249-64.
[2]. Waldinger, M.D., H.H. Berendsen, and D.H. Schweitzer, Treatment of hot flushes with mirtazapine: four case reports. Maturitas, 2000. 36(3): p. 165-8.
[3]. Garcia-Sevilla, J.A., et al., Regulation of platelet alpha 2A-adrenoceptors, Gi proteins and receptor kinases in major depression: effects of mirtazapine treatment. Neuropsychopharmacology, 2004. 29(3): p. 580-8.