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Methyldopa
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Methyldopa图片
CAS NO:555-30-6
包装:500mg
市场价:400元

产品名称
甲基多巴
L-(-)-α-Methyldopa
MK-351
产品介绍
Methyldopa (L-(-)-α-Methyldopa) 是一种 α-肾上腺素能激动剂 (对α2- adrenergic receptors有选择性)。Methyldopa 是一种前药,在中枢神经系统中被代谢 (α-Methylepinephrine)。
生物活性

Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective forα2-adrenergic receptors). Methyldopa is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

IC50& Target

α adrenergic receptor

 

体内研究
(In Vivo)

Methyldopa (L-(-)-α-Methyldopa; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].

Animal Model:60-day-old male rats[2]
Dosage:200 mg/kg
Administration:I.p.
Result:Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Clinical Trial
分子量

211.21

Formula

C10H13NO4

CAS 号

555-30-6

中文名称

卡比多巴EP杂质A

结构分类
  • Ketones, Aldehydes, Acids
来源
  • Plants
  • Hippocastanaceae
  • Aesculus hippocastanum
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.