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Sulfameter
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Sulfameter图片
CAS NO:651-06-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Sulfameter (Sulfametoxydiazine; 5-Methoxysulfadiazine) 是一种有效的长效磺胺类抗生素,具有抗菌活性。
Cas No.651-06-9
别名磺胺对甲氧嘧啶; Sulfametoxydiazine; 5-Methoxysulfadiazine
化学名4-amino-N-(5-methoxypyrimidin-2-yl)benzenesulfonamide
Canonical SMILESCOC1=CN=C(N=C1)NS(=O)(=O)C2=CC=C(C=C2)N
分子式C11H12N4O3S
分子量280.3
溶解度≥ 9.3mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sulfameter(Bayrena) is a long-acting sulfonamide antibacterial.Target: AntibacterialSulfameter(Bayrena) is a long-acting sulfonamide antibacterial. It is used as a leprostatic agent in the treatment of urinary tract infections.Six physically healthy patients each were given 2 g of sulfameter simultaneously with a high lipid, high protein and high carbohydrate test meal. This experiment was designed as a threefold crossover study, and there was a randomized assignment of patients to the different conditions. The results show that sulfameter is significantly better absorbed when administered with a high lipid meal than when given with a high protein or high carbohydrate meal, demonstrated by the areas under the serum concentration curves (AUC), by the peak serum concentration and by the cumulative renal excretion.

References:
[1]. Kaumeier S. The effect of the composition of food on the absorption of sulfameter. Int J Clin Pharmacol Biopharm. 1979 Jun;17(6):260-3.
[2]. Robins AH. Sulfameter (Sulla). Clin Pharmacol Ther. 1969 Jul-Aug;10(4):591-4.