Sulfuretin inhibits the inflammatory response by suppressing theNF-κBpathway. Sulfuretin can be used for the research of allergic airway inflammation. Sulfuretin reduces oxidative stress, platelet aggregation, and mutagenesis^[1]. Sulfuretin is a competitive and potent inhibitor of monophenolase and diphenolase activities with the IC₅₀of 13.64 μM^[2].

Sulfuretin is one of the main flavonoids produced byRhus verniciflua. Sulfuretin efficiently inhibits the infiltration of inflammatory cells and attenuates allergic airway inflammation.

Sulfuretin inhibits the inflammatory responses by suppressing the NF-κB pathway in type 1 diabetes models. Sulfuretin (40 μg/kg; single intraperitoneal injection 2 h after the last OVA challenge) suppresses ovalbumin (OVA)-induced chemotaxis and airway inflammation^[1].

270.24

Solid

C₁₅H₁₀O₅

120-05-8

硫黄菊素

• Phenols
• Polyphenols

• Plants
• Anacardiaceae
• Toxicodendron vernicifluum(Stokes) F. A. Barkl.

Room temperature in continental US; may vary elsewhere.

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)