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Hippeastrine
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Hippeastrine图片
CAS NO:477-17-8
包装与价格:
包装价格(元)
5mg电议
10mg电议
25mg电议

产品名称
小星蒜碱
产品介绍
Hippeastrine 是一种活性生物碱,对拓扑异构酶 ITop I具有良好的剂量依赖性抑制作用,IC50为7.25 μg/mL。具有抗增殖和抗癌活性。
生物活性

Hippeastrine, an active alkaloid, exhibits a good dose-dependent inhibitory effect againsttopoisomeraseI (Top I)with anIC50at 7.25 μg/mL. Antiproliferative and anticancer activities[1].

体外研究
(In Vitro)

Hippeastrine strongly inhibits the proliferation of HT-29 and Hep G2 cells in an intuitive dose-dependent manner with the IC50s at 3.98 μg/mL and 11.85 μg/mL, respectively, and also induces significant cellular morphological changes, which further validate our screening method and the potent antineoplastic effects[1].

分子量

315.32

Formula

C17H17NO5

CAS 号

477-17-8

中文名称

小星蒜碱

结构分类
  • Alkaloids
  • Pyrrole Alkaloids
来源
  • Plants
  • Amaryllidaceae
  • Narcissus tazettaLinn. var. chinensis M.Roener
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.