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Sauristolactam(Saurolactam)
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
Sauristolactam(Saurolactam)图片
CAS NO:128533-02-8
包装与价格：
包装价格(元)
250mg电议
500mg电议

产品介绍
Sauristolactam (Saurolactam) 是一种从三白草地上部分中分离出来的天然马兜铃内酰胺，对原代培养的大鼠皮质细胞中谷氨酸诱导的毒性具有显着的神经保护活性。
Cas No.128533-02-8
别名Saurolactam
Canonical SMILESO=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C
分子式C17H13NO3
分子量279.29
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].

[1]. Kim SR, et al. Aristolactam BII of Saururus chinensis attenuates glutamate-induced neurotoxicity in rat cortical cultures probably by inhibiting nitric oxide production. Planta Med. 2004 May;70(5):391-6. [2]. Li Z, et al. Saurolactam Inhibits Proliferation, Migration, and Invasion of Human Osteosarcoma Cells. Cell Biochem Biophys. 2015 Jul;72(3):719-26.