CAS NO: | 1643957-26-9 |
包装: | 100mg |
市场价: | 1080元 |
Cas No. | 1643957-26-9 |
别名 | 苄基-PEG3-乙酸叔丁酯 |
分子式 | C17H26O5 |
分子量 | 310.39 |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. [1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578. |