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Benzyl-PEG2-CH2-Boc
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Benzyl-PEG2-CH2-Boc图片
CAS NO:1643957-26-9
包装:100mg
市场价:1080元

产品介绍
Benzyl-PEG2-CH2-Boc 是一种基于PEG 的 PROTAC linker,可用于 PROTAC 的合成。
Cas No.1643957-26-9
别名苄基-PEG3-乙酸叔丁酯
分子式C17H26O5
分子量310.39
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Benzyl-PEG2-CH2-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

[1]. Ottis P, et al. Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation. ACS Chem Biol. 2017 Oct 20;12(10):2570-2578.