| CAS NO: | 76-78-8 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
| 生物活性 | Quassin (Nigakilactone D) is a bioactive triterpenoid from stem bark extract ofQuassia amara. Quassin inhibitsP. falciparumwith anIC50of 0.15 μM. Quassin possesses reversible antifertility, anti-estrogenic and anti-plasmodial activity[1][2]. | ||||||||
| IC50& Target | IC50: 0.15 μM (P. falciparum)[2] | ||||||||
| 体外研究 (In Vitro) | Quassin (Compound 1; 5-25 ng/mL) inhibits both the basal and luteinizing hormone-stimulated testosterone secretion of rat Leydig cells in a dose-dependent fashion[3]. | ||||||||
| 体内研究 (In Vivo) | Quassin (0.1-2.0 mg/kg; oral administration; daily; for 60 days; females albino rats) treatment shows a significant decrease in the weight of the ovary and uterus. And also shows a significant decrease in serum estrogen levels in quassin treated rats. The Quassin treated rats has a significantly decreased mean litter number and weight. Quassin does not adversely affect the weight of the kidney, heart, liver and the body of the rats[1].
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| 分子量 | 388.45 | ||||||||
| 性状 | Solid | ||||||||
| Formula | C22H28O6 | ||||||||
| CAS 号 | 76-78-8 | ||||||||
| 中文名称 | 苦楝树甙,苦木素 | ||||||||
| 结构分类 |
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| 来源 |
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| 运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
| 储存方式 | 4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
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