您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > hVEGF-IN-2
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
hVEGF-IN-2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
hVEGF-IN-2图片
CAS NO:186610-88-8
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
hVEGF-IN-2 (compound 19) 是选择性的VEGF(Flk-1) 受体酪氨酸激酶抑制剂,IC50值为 2.5 μM。hVEGF-IN-2 抑制 PDGF 受体酪氨酸激酶活性,IC50值为 33.1 μM。hVEGF-IN-2 可用于开发受体酪氨酸激酶特异性药物。
生物活性

hVEGF-IN-2 (compound 19) is a selectiveVEGF(Flk-1)receptor tyrosine kinases(RTK) inhibitor with anIC50value of 2.5 μM. hVEGF-IN-2 inhibitsPDGFRTK activity with anIC50value of 33.1 μM. hVEGF-IN-2 can be used for the development of RTK-specific drugs[1].

IC50& Target

VEGFR1

2.5 μM (IC50)

PDGF

33.1 μM (IC50)

体外研究
(In Vitro)

hVEGF-IN-2 (0-100 μM) shows the inhibitory activities to particular RTKs at the cellular level with IC50values of 2.5, 33.1, >100, >100 and >100 nM for VEGF, PDGF, EGF, HER-2 and IGF-1, respectively[1].

分子量

306.36

Formula

C19H18N2O2

CAS 号

186610-88-8

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.