CAS NO: | 93413-69-5 |
包装 | 价格(元) |
5mg | 电议 |
10mg | 电议 |
25mg | 电议 |
生物活性 | Venlafaxine (Wy 45030) is an orally active, potentserotonin (5-HT)/norepinephrine (NE)reuptake dual inhibitor. Venlafaxine is an antidepressant[1]. | ||||||||
体外研究 (In Vitro) | Venlafaxine (Wy 45030) dose-dependently inhibits binding of the serotonin transporter radioligand [3H]-paroxetine to membranes from cells transfected with the human 5-HT transporter with a Kiof 2.48 μM. Venlafaxine inhibits binding of the NE transporter ligand [3H]-nisoxetine to membranes from cells transfected with the human NE transporter with a Kiof 82 nM[1]. | ||||||||
体内研究 (In Vivo) | Venlafaxine (Wy 45030; 10-100 mg/kg; IP) dose-dependently blocks the depletion of norepinephrine levels in rat hypothalamus induced by 6-OHDA[1].
| ||||||||
Clinical Trial | |||||||||
分子量 | 277.40 | ||||||||
Formula | C17H27NO2 | ||||||||
CAS 号 | 93413-69-5 | ||||||||
中文名称 | 文拉法辛 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |