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Oxfendazole
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxfendazole图片
CAS NO:53716-50-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
奥芬达唑是芬苯达唑的亚砜形式,是一种广谱苯并咪唑驱虫药。
Cas No.53716-50-0
别名奥芬哒唑
化学名methyl N-[6-(benzenesulfinyl)-1H-benzimidazol-2-yl]carbamate
Canonical SMILESCOC(=O)NC1=NC2=C(N1)C=C(C=C2)S(=O)C3=CC=CC=C3
分子式C15H13N3O3S
分子量315.35
溶解度≥ 15.75mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Oxfendazole is the sulfoxide form of fenbendazole which is a broad spectrum benzimidazole anthelmintic. Target: AntiparasiticOxfendazole is the sulfoxide form of fenbendazole, a broad spectrum benzimidazole anthelmintic. Its main use is for protecting livestock against roundworm, strongyles and pinworms.[1]. Pigs in the treated group received Oxfendazole orally at 30 mg/kg dose. At five days post-treatment, animals were sacrificed and the clinical efficacy of the Oxfendazole treatment was established following the currently available WAAVP guidelines for a controlled efficacy test. None of the animals involved in this experiment showed any adverse events during the study. Oxfendazole treatment given as a single 30 mg/kg oral dose showed a 100% efficacy against all the nematode parasites present in the three experiments. In conclusion, under the current experimental conditions, Oxfendazole orally administered to naturally parasitized piglets at a single dose of 30 mg/kg was safe and highly efficacious (100%) against adult stages of A. suum, Oesophagostomum spp., T. suis and Metastrongylus spp [1].

References:
[1]. http://www.chemicalland21.com/lifescience/phar/OXFENDAZOLE.htm
[2]. Alvarez, L., et al., Efficacy of a single high oxfendazole dose against gastrointestinal nematodes in naturally infected pigs. Veterinary parasitology, 2013. 194(1): p. 70-74.