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Urocanic acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Urocanic acid图片
CAS NO:104-98-3
包装:1g
市场价:450元

产品介绍
Urocanicacid是皮肤中的主要光线受体,天然以反式尿刊酸存在。
Cas No.104-98-3
别名尿刊酸
Canonical SMILESO=C(O)/C=C/C1=CN=CN1
分子式C6H6N2O2
分子量138.12
溶解度DMSO: 125 mg/mL (905.01 mM); Water: 2 mg/mL (14.48 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Urocanic acid, produced in the upper layers of mammalian skin, is a major absorber of ultraviolet radiation (UVR).

Urocanic acid (UCA) is formed in the upper layers of the epidermis where filaggrin, a histidine-rich filamentous protein produced after caspase-14 cleavage of profilaggrin, is broken down by proteinases into component amino acids[1].

[1]. Gibbs NK, et al. Recent advances in urocanic acid photochemistry, photobiology and photoimmunology. Photochem Photobiol Sci. 2008 Jun;7(6):655-67.