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LNK754
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
LNK754图片
CAS NO:439153-64-7
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议
20mg电议

产品介绍
LNK754 是 CP-609754 的外消旋体。
Cas No.439153-64-7
别名(Rac)-LNK-754; (Rac)-OSI-754
Canonical SMILESO=C1N(C)C2=C(C=C(C(O)(C3=CC=C(Cl)C=C3)C4=CN=CN4C)C=C2)C(C5=CC=CC(C#C)=C5)=C1
分子式C29H22ClN3O2
分子量479.96
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

LNK754 is a farnesyltransferase inhibitor, used for the treatment of cancer and Alzheimer's disease.

LNK-754 (0.9 mg/kg) significantly reduces α-synuclein plaques in a mouse model of PD, APP(SL), at 6 months of age for 3 months[1].

[1]. Keith T Gagnon. HD Therapeutics-CHDI Fifth Annual Conference. IDrugs. 2010 Apr;13(4):219-23.