| CAS NO: | 830-96-6 |
| 包装: | 1g |
| 市场价: | 446元 |
| Cas No. | 830-96-6 |
| 别名 | 吲哚-3-丙酸,Indole-3-propionic acid; 3-IPA |
| Canonical SMILES | C1=CC=CC2=C1C(=C[NH]2)CCC(O)=O |
| 分子式 | C11H11NO2 |
| 分子量 | 189.21 |
| 溶解度 | DMSO: ≥ 100 mg/mL (528.51 mM); Water: 1 mg/mL (5.29 mM; ultrasonic and warming and heat to 80℃) |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer's disease[1]. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds[2]. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function[3]. [1]. Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3698-703. [2]. Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24. [3]. de Mello VDet al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Sci Rep. 2017 Apr 11;7:46337. doi: 10.1038/srep46337. |
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