Spironolactone-d3-1 is deuterium labeled Spironolactone. Spironolactone (SC9420) is an orally active aldosteronemineralocorticoid receptor antagonistwith an IC50 of 24 nM. Spironolactone is also a potent antagonist ofandrogen receptorwith an IC50 of 77 nM. Spironolactone promotesautophagyin podocytes^[1][2][3].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

419.59

C₂₄H₂₉D₃O₄S

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.