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4-Hydroxymephenytoin D3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
4-Hydroxymephenytoin D3图片
CAS NO:1173022-56-4
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议

产品介绍
4-Hydroxymephenytoin D3 是 4-Hydroxymephenytoin 的氘代物。4-Hydroxymephenytoin 是抗癫痫药 mephenytoin 的代谢物; mephenytoin 为 CYP2C19 的一种配体。
生物活性

4-Hydroxymephenytoin D3 is the deuterium labeled 4-Hydroxymephenytoin. 4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate[1][2].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

237.27

性状

Solid

Formula

C12H11D3N2O3

CAS 号

1173022-56-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
溶解性数据
In Vitro: 

DMSO : 100 mg/mL(421.46 mM;Need ultrasonic)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM4.2146 mL21.0730 mL42.1461 mL
5 mM0.8429 mL4.2146 mL8.4292 mL
10 mM0.4215 mL2.1073 mL4.2146 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。