CAS NO: | 1401-55-4 |
包装 | 价格(元) |
10 mM * 1 mL in DMSO | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
10 g | 电议 |
50 g | 电议 |
生物活性 | Tannic acid is a novelhERG channelblocker withIC50of 3.4 μM. | ||||||||||||||||
IC50& Target | IC50: 3.4 μM (hERG channel)[1] | ||||||||||||||||
体内研究 (In Vivo) | During the course of treatment, tannic acid significantly ameliorates these phenotypes in AD skin lesions. Tannic acid treatment aslo reduces these dermal changes compare with AD mice. Treatment with tannic acid increases PPARγ expression in AD skin sections. The PPARγ protein expression is suppressed in vehicle-treated AD mice, but when treats with tannic acid, its expression is increased dramatically. The IL-1β, TNFα, TNFR1, and COX2 protein expressions are significantly up-regulated in vehicle-treated AD mice, but significantly suppressed by tannic acid treatment[2]. | ||||||||||||||||
Clinical Trial | |||||||||||||||||
分子量 | 1701.20 | ||||||||||||||||
性状 | Solid | ||||||||||||||||
Formula | C76H52O46 | ||||||||||||||||
CAS 号 | 1401-55-4 | ||||||||||||||||
中文名称 | 鞣酸;单宁酸;丹宁酸;没食子鞣酸 | ||||||||||||||||
结构分类 |
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来源 |
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运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||||||
储存方式 |
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溶解性数据 | In Vitro: H2O : ≥ 100 mg/mL(58.78 mM) DMSO : 100 mg/mL(58.78 mM;Need ultrasonic) *"≥" means soluble, but saturation unknown. 配制储备液
* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效。 In Vivo: 请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液,再依次添加助溶剂: ——为保证实验结果的可靠性,澄清的储备液可以根据储存条件,适当保存;体内实验的工作液,建议您现用现配,当天使用;
以下溶剂前显示的百
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