8-Bromo-ATP (8-Bromoadenosine 5'-triphosphate), an ATP analogue, is a purinergicP2X receptoragonist. 8-Bromo-ATP shows cytotoxic to multiple myeloma cells with anIC₅₀of 23.1 μM^[1][2][3].

8-Bromo-ATP (10-50 μM; 5 days) treatment shows cytotoxic to multiple myeloma^[3].
Fluorescence measurements are made possible through the use of 8-Bromo-ATP, which selectively quenched certain tryptophan residues of the ATPase. 8-Bromo-ATP enhances the rate of dephosphorylation of native ATPase 2-3-fold when added in the absence of divalent cations^[2].

586.08

C₁₀H₁₅BrN₅O₁₃P₃

23567-97-7

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