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Atazanavir-d9
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Atazanavir-d9图片
CAS NO:1092540-51-6
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品名称
BMS-232632-d9
产品介绍
Atazanavir-d9 (BMS-232632-d9) 是 Atazanavir 的氘代物。Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂,用于艾滋病毒感染的研究。Atazanavir 是CYP3A4的底物和抑制剂,也是P-糖蛋白的抑制剂和诱导剂。Atazanavir 也是SARS-CoV 3CLpro的抑制剂,IC50为 3.49 μM。
生物活性

Atazanavir-d9 (BMS-232632-d9) is the deuterium labeled Atazanavir. Atazanavir (BMS-232632), a highly selectiveHIV-1proteaseinhibitor, is the first protease inhibitor approved for once-daily administration[1]. Atazanavir (BMS-232632) is a substrate and inhibitor ofCYP3A4, and an inhibitor and inducer ofP-glycoprotein(P-gp)[2]. Atazanavir is also aSARS-CoV3CLproinhibitor with anIC50of 3.49 μM[3].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

713.91

Formula

C38H43D9N6O7

CAS 号

1092540-51-6

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.