TLR9-IN-1 is a potent and selectiveTLR9inhibitor with anIC₅₀value of 7 nM for humanTLR9. TLR9-IN-1 can be used for researching diseases associated with undesirable immune response^[1].

TLR9-IN-1 (compound no.29) (0-10 μM; 24 h) exhibits moderately inhibitory activity against IL-1b with an IC₅₀of 1.61 μM in human monocytes (co-incubated with TLR8 agonist ORN8L, RNA oligonucleotide)^[1].

421.54

C₂₃H₃₁N₇O

2226366-86-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.