AACOCF3 (Arachidonyl Trifluoromethyl Ketone), an inhibitor of cytosolic phospholipase A2 (IC50 =15 μM), is arachidonic acid derivative where the carboxyl group is replaced by a trifluoromethyl ketone group. It inhibits the activity of the 85 kDa cPLA2 and the 80 kDa macrophage iPLA2 without altering the activity of the 14 kDa sPLA2s. ATK is useful for differentiating the effects of cPLA2 and iPLA2 from sPLA2.

纯度：≥98%

CAS：149301-79-1