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S-(+)-Etomoxir
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
S-(+)-Etomoxir图片
CAS NO:828934-40-3
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议

产品介绍

S-(+)-Etomoxir, S-isomer of etomoxir, is a novel and potent inhibitor of CPT1 (carnitine palmitoyltransferase A), which is required for the oexidation of long-chain acyl CoA esters. Etomoxir is an irreversible inhibitor of carnitine palmitoyltransferase-1 (CPT-1) on the outer face of the inner mitochondrial membrane. It inhibits β-oxidation in mitochondria; shown to inhibit cardiolipin biosynthesis from exogenous fatty acid in H9c2 cells. Etomoxir has also been identified as a direct agonist of PPARα. Etomoxir is a compound that binds irreversibly to the catalytic site of CPT-1 inhibiting its activity, but also upregulates fatty acid oxidation enzymes.

纯度:≥98%

CAS:828934-40-3