MRS2365 is a potent and selectiveP2Y1 receptoragonist with anEC₅₀of 0.4 nM. MRS2365 shows little agonist or antagonist activity at the P2Y12 or P2Y13 receptors^[1][2].

Selective activation of the P2Y1 receptor also is suggested from functional studies of human platelets as MRS2365 potently induced shape change without causing the sustained aggregation that is a hallmark of simultaneous activation of the P2Y1 and P2Y12 receptors by ADP or by previously studied ADP analogues^[2].

483.33

C₁₃H₁₉N₅O₉P₂S

436847-09-5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.