CTAP TFA is a potent, highly selective, and BBB penetrantμopioid receptorantagonist, with anIC₅₀of 3.5 nM. CTAP TFA displays over 1200-fold selectivity overδ opioid(IC₅₀=4500 nM) andsomatostatin receptors. CTAP TFA can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction^[1][2].

CTAP TFA (0-1 mg/kg, IP, single) blocks morphine’s antinociceptive effect^[1].
CTAP TFA (10 mg/kg; IP, single) has no effect on L-DOPA-induced limb, axial, orolingual, or locomotor abnormal involuntary movements^[1].
CTAP TFA is stable in the blood and serum of rats (T_1/2>500 min), showing that the structure of this peptide offers enzymatic resistance^[2].
CTAP TFA is extensively protein-bound to albumin in the perfusion medium (68.2%) and to proteins in rat serum (84.2%)^[2].

1218.32

Solid

C₅₃H₇₀F₃N₁₃O₁₂S₂

Phe-Cys-Tyr-Trp-Arg-Thr-Pen-Thr-NH2 (Disulfide bridge:Cys2-Pen7)

FCYWRT{Pen}T-NH2 (Disulfide bridge:Cys2-Pen7)

Room temperature in continental US; may vary elsewhere.

Sealed storage, away from moisture and light, under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under nitrogen)

H₂O : 100 mg/mL(82.08 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture and light, under nitrogen)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。