Peptide YY (pig) is a 36 amino acid gastrointestinal peptide, can be isolated from porcine duodenum. Peptide YY (pig) decreases appetite and food-intake by activation of theY2 receptor. Peptide YY (pig) is present mainly in pancreatic endocrine cells with effect on both intestinal motility and the cardiovascular system^[1][2][3].

Peptide YY (pig) (10 μg/mL) 和人类胰多肽 (PP) 一样具有抗体特异性，即对 PYY 抗血清特异，两者都可能在各种脊椎动物胰岛激素分泌的调节中发挥内分泌或旁分泌作用^[2]。

Peptide YY_1-36(pig) 会被二肽基肽酶 IV (DPP-IV) 降解为 PYY_3-36。PYY_3-36(50 nmol/kg; 静脉注射; 单剂量) 在哥根廷迷你猪和恒河猴中会进一步分解为许多代谢产物^[3]。
Peptide YY_1-36(pig) 具有减缓肠道转运、抑制胃肠道负离子和电解质分泌、降低血糖等其他生理作用^[3]。

4240.72

C₁₉₀H₂₈₈N₅₄O₅₇

81858-94-8

YPAKPEAPGEDASPEELSRYYASLRHYLNLVTRQRY-NH2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.