MK-0493 is a potent, orally active and selective agonist of themelanocortin receptor4 (MC4R), demonstrating significant reductions in energy intake^[1].

MK-0493 dose-dependently increases electrically evoked increases in ICP^[2].
MK-0493 is shown to promote robust weight loss activity following oral administration in preclinical animal models, suggesting the drug can access the target site in the hypothalamus^[3].

546.09

Solid

C₃₀H₃₈ClF₂N₃O₂

455956-93-1

Room temperature in continental US; may vary elsewhere.

DMSO : 100 mg/mL(183.12 mM;Need ultrasonic)

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